discusses approximate and exact tests for GO enrichment/depletion, the associated p-value computations, and Table 1 contains over 20 GO tools packages.
Bioinformatics 2007 23(4):401-407
http://bioinformatics.oxfordjournals.org/cgi/content/full/23/4/401
The authors at Cold Spring Harbor Laboratory functionally identify chromodomain helicase DNA binding domain 5 (Chd5) as a tumor suppressor that controls proliferation, apoptosis, and senescence via the p19Arf/p53 pathway. They demonstrate that Chd5 functions as a tumor suppressor in vivo and implicate deletion of CHD5 in human cancer.
Cell, Vol 128, 459-475, 09 February 2007
